Young Boys managed to cause an upset in Group I as Guillaume Hoarau and Leonardo Bertone both scored in a 2-0 victory over Napoli.
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Everton continued a promising start to their Europa League campaign by claiming a potentially crucial point in a goalless draw with Lille.
Kevin De Bruyne starred elsewhere in Group H as Wolfsburg recorded a 4-2 win over Krasnodar, who remain bottom of the group.
Andrej Kramaric stole the show for Rijeka as he netted a hat-trick to guide Rijeka to a 3-1 victory over Group G rivals Feyenoord.
In the same group, Sevilla held on to top spot by playing out a goalless draw with Standard Liege in Belgium.
Aalborg boosted their chances of reaching the next round with a 2-0 victory over Dynamo Kiev in Group J, where there was also success for Steaua Bucuresti, who claimed a 2-1 win over Rio Ave thanks to a brace from Raul Rusescu.
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In Group K, Dinamo Minsk earned their first point of the campaign by holding Guingamp to a goalless draw, while Juan Vargas kept up Fiorentina's 100% record with the winner in a 1-0 triumph over PAOK.
Mustafa Yatabare and Kevin Constant both struck in the second half to guide Trabzonspor to a 2-0 success against Lokeren.
