Liverpool will be looking to move themselves one step closer to the Premier League when they lock horns with Everton in the Merseyside derby at Anfield on Wednesday night.
Manchester City, Newcastle United and Aston Villa are among the other Premier League teams in action, and Barcelona face Atletico Madrid in the second leg of their Copa del Rey semi-final, while there are other fixtures taking place in the Championship, Eredivisie, Primeira Liga, Coppa Italia, DFB-Pokal, League Two and the CONCACAF Champions Cup.
Below is Sports Mole's selection of predictions and previews for today's and tomorrow's fixtures.