AC Milan manager Sinisa Mihajlovic has made no changes to the side that lost 1-0 to Inter Milan last weekend.
Mario Balotelli starts on the bench again while Carlos Bacca and Luiz Adriano keep their place up front.
Palermo make four changes to the side that drew 2-2 with Capri last Saturday.
Roberto Vitiello makes way for Aljaz Struna in defence, while Uros Djurdjevic spearheads the attack for the visitors.
AC Milan: Lopez; Abate, Zapata, Romagnoli, De Sciglio; Kucka, Montolivo, Bonaventura; Honda; Bacca, Luiz Adriano.
Subs: Abbiati, Donnarumma, Alex, Calabria, Rodrigo Ely, De Jong, José Mauri, Nocerino, Poli, Suso, Balotelli, Cerci.
Palermo: Sorrentino; Struna, Gonzalez, El Kaoutari; Hiljemark, Jajalo, Chochev, Lazaar; Vazquez, Quaison, Djurdjevic
Subs: Vitiello, Rispoli, Andjelkovic, Goldaniga, Trajkovski, Cassini, Gilardino, Brugman, Maresca, Rigoni, Daprela, Colmbi
