Boasting a three-goal first-leg advantage, Arsenal will be looking to finish the job and secure their spot in the Champions League semi-finals when they face Real Madrid at the Santiago Bernabeu in Wednesday's second leg.
Inter Milan welcome Bayern Munich to San Siro for their second-leg showdown, while in the Premier League, Newcastle United will climb up to third in the table if they beat Crystal Palace at St James' Park.
Below is Sports Mole's selection of predictions and previews for today's and tomorrow's fixtures.